What hand feature is typically seen in infants with trisomy 18?

What hand feature is typically seen in infants with trisomy 18?

• A. Straight fingers
• B. Clenched hands
• C. Webbed fingers
• D. Missing digits

Answer: (B)

Infants with trisomy 18, also known as Edwards syndrome, commonly exhibit clenched hands as a distinct characteristic. This feature arises from the underlying abnormalities in muscle tone and skeletal development typically associated with this genetic condition. The clenched hands often have a specific posture, with the fingers tightly flexed, which is particularly notable in these infants.

Trisomy 18 is characterized by several physical anomalies, but the clenched hand position is one of the primary signs that can assist in making a clinical diagnosis. This trait is due to central nervous system abnormalities that result in decreased motor function and atypical muscle tone. While other hand features like straight fingers, webbed fingers, and missing digits can be associated with different genetic disorders or conditions, the specificity of clenched hands in the context of trisomy 18 is well-documented and serves as an important clinical indicator.